Intraocular tolerance to silicone oils of different specific gravities. An experimental study.

Eckardt, C., Schmidt, D. and Czank, M. (1990) Intraocular tolerance to silicone oils of different specific gravities. An experimental study. Ophthalmologica, 201 (3). pp. 133-9.

Full text not available from this repository.

Abstract

Different methylphenylsilicone (MPS) and fluorosilicone (FS) oils having a higher specific gravity than water were investigated as vitreous replacements. Their intraocular tolerance in vitrectomized aphakic rabbit eyes was evaluated for periods of up to 4 months and compared to that of regular polydimethylsilicone oil (PDMS). Weakly fluorinated FS and weakly phenylated MPS showed a presumably toxic effect on the retina. As compared to highly fluorinated FS, highly phenylated MPS showed better intraocular tolerance; however, inflammatory reaction was slightly more extensive than in eyes filled with PDMS.

Document Type: Article
Additional Information: Eckardt, C Schmidt, D Czank, M Comparative Study Switzerland Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde Ophthalmologica. 1990;201(3):133-9.
Keywords: Animals Corneal Edema/chemically induced/pathology Dimethylpolysiloxanes/toxicity Follow-Up Studies Inflammation/chemically induced/pathology Iris/drug effects/pathology Rabbits Retina/*drug effects/pathology Retinal Detachment/chemically induced/pathology Silicone Oils/*toxicity Silicones/toxicity Siloxanes/toxicity Specific Gravity *Vitrectomy
Research affiliation: Kiel University
Refereed: No
ISSN: 0030-3755 (Print) 0030-3755 (Linking)
Date Deposited: 02 Feb 2012 07:44
Last Modified: 08 Oct 2012 07:33
URI: http://oceanrep.geomar.de/id/eprint/15510

Actions (login required)

View Item View Item