Phytochemistry of the genus Skimmia (Rutaceae).

Epifano, Francesco, Fiorito, Serena, Genovese, Salvatore, Granica, Sebastian, Vitalini, Sara and Zidorn, Christian (2015) Phytochemistry of the genus Skimmia (Rutaceae). Phytochemistry, 115 . pp. 27-43. DOI 10.1016/j.phytochem.2015.02.014.

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The genus Skimmia is a rich source of interesting secondary metabolites, including 20 alkaloids derived from anthranilic acid, 45 coumarins, 21 limonoids, four cholestane derivatives, six pentacyclic triterpenes, six flavonoids, and two unusual fatty acid derivatives. Skimmia is employed in folk medicine e.g. against fever, inflammations, and rheumatism. Skimmia extracts, Skimmia essential oils and pure compounds isolated from Skimmia extracts have been experimentally shown to have various bioactivities such as antioxidant, anti-inflammatory, antimicrobial, and insecticidal.

In this review we discuss the exact structures of compounds isolated from members of the genus Skimmia, bioactivities of Skimmia extracts and pure compounds derived from them, and systematic implications of the patterns of occurrence of these compounds. Moreover, research gaps and interesting avenues for future research are discussed briefly.

Document Type: Article
Research affiliation: Kiel University > Kiel Marine Science
Refereed: Yes
DOI etc.: 10.1016/j.phytochem.2015.02.014
ISSN: 0031-9422
Date Deposited: 29 Jun 2017 09:23
Last Modified: 01 Feb 2018 13:29

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