Marine bacteria and fungi as promising source for new antibiotics.

Wiese, Jutta and Imhoff, Johannes F. (2019) Marine bacteria and fungi as promising source for new antibiotics. Drug Development Research, 80 (1). pp. 24-27. DOI 10.1002/ddr.21482.

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Abstract

Natural products and derivatives thereof are of considerable importance in the discovery of new pharmaceuticals, for example, for the treatment of cancer, diabetes, inflammation diseases, and infection diseases caused by bacteria, fungi, viruses, or parasites. The great biodiversity of marine microorganisms is reflected in their huge chemical diversity, which provides a rich source of biologically active compounds. An increasing interest in marine microorganisms as promising producers of new compounds with potential medical applications has raised increasing interest in the sustainable exploration of marine microbial resources for the discovery of new antibiotics, which is highlighted. The bottlenecks in the development of drugs using the large marine natural product pipeline are also discussed.

Document Type: Article
Funder compliance: info:eu-repo/grantAgreement/EC/FP7/265926
Keywords: antibiotics; biodiscovery; marine bacteria; marine fungi; marine natural products
Research affiliation: OceanRep > GEOMAR > FB3 Marine Ecology > FB3-MI Marine Microbiology
Refereed: Yes
Open Access Journal?: No
DOI etc.: 10.1002/ddr.21482
ISSN: 0272-4391
Projects: Marine Fungi
Date Deposited: 09 Nov 2018 13:04
Last Modified: 08 Mar 2019 07:50
URI: http://oceanrep.geomar.de/id/eprint/44639

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