Seaweeds to the rescue of forgotten diseases: a review.

Freile-Pelegrín, Yolanda and Tasdemir, Deniz (2019) Seaweeds to the rescue of forgotten diseases: a review. Botanica Marina, 62 (3). pp. 211-226. DOI 10.1515/bot-2018-0071.

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Abstract

Neglected tropical diseases (NTDs) are a group of diseases that are predominant in the poorest parts of the world affecting 1.4 billion people. The development of new drugs is urgently needed in order to combat these forgotten diseases. Natural products from marine organisms have been widely explored as a source of new bioactive molecules. However, despite their enormous potential in drug discovery, not even one seaweed-based molecule has entered pre-clinical testing for NTDs. This review gives an overview of the current status of algal natural products against NTDs. The list of compounds is by no means exhaustive, but covers the most important classes of active substances in marine algae against the most studied NTDs.

Document Type: Article
Keywords: insect-borne infections; leishmaniasis; neglected tropical diseases; seaweed; trypanosomiasis
Research affiliation: OceanRep > GEOMAR > Applied R&D > GEOMAR-Biotech
OceanRep > GEOMAR > FB3 Marine Ecology > FB3-MN Marine natural products chemistry
Refereed: Yes
Open Access Journal?: No
DOI etc.: 10.1515/bot-2018-0071
ISSN: 0006-8055
Date Deposited: 26 Mar 2019 13:08
Last Modified: 27 Jun 2019 08:25
URI: http://oceanrep.geomar.de/id/eprint/46216

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