Antibacterial activity of marine bacterium Pseudomonas sp. associated with soft coral Sinularia polydactyla against Streptococcus equi subsp. zooepidemicus.

Radjasa, O. K., Salasia, S. I. O., Sabdono, A., Wiese, Jutta , Imhoff, Johannes F. , Lämmler, C. and Risk, M. J. (2007) Antibacterial activity of marine bacterium Pseudomonas sp. associated with soft coral Sinularia polydactyla against Streptococcus equi subsp. zooepidemicus. Open Access International Journal of Pharmacology, 3 (2). pp. 170-174. DOI 10.3923/ijp.2007.170.174.

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Abstract

A marine bacterium associated with soft coral Sinularia polydactyla collected from Bandengan water, Jepara, North Java Sea, Indonesia, was successfully screened for antibacterial activity against pathogenic bacterium Streptococcus equi subsp. zooepidemicus K6.72 isolated from infected monkey of the island of Bali and identified based on morphological, biochemical and molecular methods. Marine bacterium was identified as Pseudomonas sp. based on its 16S rDNA and was found to amplify gene fragments of Non-ribosomal peptide synthetase (NRPS). Cloning and subsequent sequencing, a 360 bp long DNA fragment was obtained and the deduced amino acid sequence showed conserved signature regions for peptide synthetases and revealed a high similarity of 61.1% to genes peptide synthetase of Bacillus subtilis

Document Type: Article
Keywords: Screening, soft coral-associated bacteria, secondary metabolites
Research affiliation: OceanRep > The Future Ocean - Cluster of Excellence
OceanRep > GEOMAR > FB3 Marine Ecology > FB3-MI Marine Microbiology
Refereed: Yes
Open Access Journal?: Yes
DOI etc.: 10.3923/ijp.2007.170.174
ISSN: 1811-7775
Projects: Future Ocean
Date Deposited: 03 Dec 2008 16:51
Last Modified: 23 Sep 2019 23:05
URI: http://oceanrep.geomar.de/id/eprint/51

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