Nuclear gene indicates coat-color polymorphism in mammoths.

Römpler, Holger, Rohland, Nadin, Lalueza-Fox, Carles, Willerslev, Eske, Kuznetsova, Tatyana, Rabeder, Gernot, Bertranpetit, Jaume, Schöneberg, Torsten and Hofreiter, Michael (2006) Nuclear gene indicates coat-color polymorphism in mammoths. Science, 313 (5783). p. 62. DOI 10.1126/science.1128994.

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Supplementary data:


By amplifying the melanocortin type 1 receptor from the woolly mammoth, we can report the complete nucleotide sequence of a nuclear-encoded gene from an extinct species. We found two alleles and show that one allele produces a functional protein whereas the other one encodes a protein with strongly reduced activity. This finding suggests that mammoths may have been polymorphic in coat color, with both dark- and light-haired individuals co-occurring.

Document Type: Article
Keywords: Ancient DNS research; Large-scale extraction; Multiplex polymerase chain reaction; PCR; Mammoth; Coat-colour; Pleistocene
Refereed: Yes
Publisher: American Association for the Advancement of Science (AAAS)
Projects: Laptev Sea System, Permafrost
Date Deposited: 17 Mar 2015 10:22
Last Modified: 01 Jan 2016 00:38

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