Mackinder, Luke, Wheeler, Glen, Schroeder, Declan, Riebesell, Ulf and Brownlee, Colin (2010) Molecular Mechanisms Underlying Calcification in Coccolithophores. Geomicrobiology Journal, 27 (6). pp. 585-595. DOI 10.1080/01490451003703014.

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Abstract

A number of studies are providing increasing genomic and transcriptomic information on the molecular components of transport, and biochemical control in the cell biology of calcification in coccolithophores. In this review we summarise recent evidence for molecular components involved in the trans-cellular transport of Ca2+, inorganic carbon and H+ between the external medium and the intracellular calcification compartment. We present new hypotheses for the transport of substrates to the site of calcification and for the removal of products, highlighting key gaps in our current knowledge. We also discuss how a cellular and molecular approach will improve abilities to understand and predict responses and adaptation to changing ocean chemistry of this important group of microorganisms.

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