Langfeldt, Daniela, Neulinger, Sven C., Heuer, Wieland, Staufenbiel, Ingmar, Kuenzel, Sven, Baines, John F., Eberhard, Joerg and Schmitz, Ruth A. (2014) Composition of Microbial Oral Biofilms during Maturation in Young Healthy Adults. PLoS ONE, 9 (2). DOI 10.1371/journal.pone.0087449.

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Abstract

In the present study we aimed to analyze the bacterial community structure of oral biofilms at different maturation stages in young healthy adults. Oral biofilms established on membrane filters were collected from 32 human subjects after 5 different maturation intervals (1, 3, 5, 9 and 14 days) and the respective phylogenetic diversity was analyzed by 16S rDNA amplicon sequencing. Our analyses revealed highly diverse entire colonization profiles, spread into 8 phyla/candidate divisions and in 15 different bacterial classes. A large inter-individual difference in the subjects' microbiota was observed, comprising 35% of the total variance, but lacking conspicuous general temporal trends in both alpha and beta diversity. We further obtained strong evidence that subjects can be categorized into three clusters based on three differently occurring and mutually exclusive species clusters.

Document Type:	Article
Additional Information:	Times Cited: 1 Baines, John/B-3580-2010 0 1
Research affiliation:	OceanRep > The Future Ocean - Cluster of Excellence > FO-R08 Kiel University > Kiel Marine Science OceanRep > The Future Ocean - Cluster of Excellence Kiel University
Refereed:	Yes
Open Access Journal?:	No
Publisher:	Public Library of Science
Projects:	Future Ocean
Date Deposited:	30 Mar 2015 12:31
Last Modified:	29 Jun 2019 13:21
URI:	https://oceanrep.geomar.de/id/eprint/27792

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