Lamprecht, C., Taale, M., Paulowicz, I., Westerhaus, H., Grabosch, C., Schuchardt, A., Mecklenburg, M., Bottner, M., Lucius, R., Schulte, K., Adelung, Rainer and Selhuber-Unkel, C. (2016) A Tunable Scaffold of Microtubular Graphite for 3D Cell Growth. Acs Applied Materials & Interfaces, 8 (24). pp. 14980-14985. DOI 10.1021/acsami.6b00778.

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Abstract

Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting bioengineering possibilities such as the generation of an artificial extracellular matrix. Here we have explored the feasibility and potential of AG as a scaffold for 3D cell growth employing cyclic RGD (cRGD) peptides coupled to poly(ethylene glycol) (PEG) conjugated phospholipids for surface functionalization to promote specific adhesion of fibroblast cells. Successful growth and invasion of the bulk material was followed over a period of 4 days.

Document Type:	Article
Additional Information:	Times Cited: 1 Lamprecht, Constanze Taale, Mohammadreza Paulowicz, Ingo Westerhaus, Hannes Grabosch, Carsten Schuchardt, Arnim Mecklenburg, Matthias Boettner, Martina Lucius, Ralph Schulte, Karl Adelung, Rainer Selhuber-Unkel, Christine Si
Keywords:	aerographite tissue engineering 3D scaffold cyclic RGD fibroblasts
Research affiliation:	Kiel University > Kiel Marine Science OceanRep > The Future Ocean - Cluster of Excellence
Refereed:	Yes
Open Access Journal?:	No
Publisher:	American Chemical Society
Projects:	Future Ocean
Date Deposited:	18 Mar 2017 12:12
Last Modified:	27 May 2019 11:21
URI:	https://oceanrep.geomar.de/id/eprint/36183

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